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RESEARCH & PUBLICATIONS
5.1     RESEARCH AREAS

1. Intraluminal oesophageal impedance and pH in the assessment of gastro-oesophageal reflux and temporal causal relationship with cardio-respiratory events in a randomised placebo-controlled study of esomeprazole in preterm and term neonates. Head of multi-disciplinary research team. MD supervision. External funding.

2. Confocal endomicroscopy in the non-biopsy assessment of mucosal pathology in paediatric enteropathy, ileo-colitis, and polyp syndromes. MD supervision. External funding.

3. Interventional therapeutic anti-reflux endoscopy for the treatment of gastro-oesophageal reflux of childhood.

4. Endoscopic pyloromyotomy for the treatment of pyloric stenosis in childhood.

5. Prophylactic intervention with the anti-fibroblastic agent mitomycin C for the prevention of caustic ingestion-associated oesophageal stricture formation in children.

6. Use of a novel propulsion agent, tegaserod, in the treatment of GORD in infants and children. Proposed external funding under consideration.

7. Double balloon enteroscopy in the assessment of small bowel mucosal pathology in children.

8. Genomic mapping in Barrett’s oesophagus in childhood. External funding.

(For all listed from 1. to 8. see research grants below)

5.2     RESEARCH GRANTS AND CONTRACTS

1. Egyptian Consulate Educational Grant. Thomson M. 2006-8. £9,600.
2. Multi-centre randomised Anti-Interleukin 5 trial for childhood eosinophilic oesophagitis. Glaxo-Smith-Kline. 2006-2007. £14,000. Thomson M.
3. Sheffield Children’s Hospital Charity Appeal funding for research and educational grant for colonoscopy training. Scope-guide, magnetic coil colonoscope and Evis Lucera processor system. 2006. £134,000. Thomson M. (Not strictly a Grant as not peer-reviewed at that time.)
4. Confocal endo-microscopic analysis in paediatric ulcerative colitis and Crohn’s disease. Westfield Foundation. 2006. £51,000. Hurlstone DP, Thomson M..
5. Pentax educational grant: confocal endomicroscopy in ulcerative colitis and Crohn’s disease. 2006. £12,000. Hurlstone DP, Thomson M..
6. Esomeprazole and neonatal gastro-oesophageal reflux: assessment with combined intraluminal impedance and video-cardiorespiratory analysis. Astra-Zeneca. 2006-2008. £330,000. Thomson M, Coombs R.
7. Confocal endoscopic microscope Award. South Yorkshire Cancer Charitable Trust. 2006. £65,000.
Double Balloon Enteroscopy Award.Westfield Foundation, Sheffield. 2005. £53,000. Hurlstone DP, Thomson M.
8. Sheffield Children’s Hospital Charity Appeal funding for study: genomic instability in paediatric Barrett’s oesophagus. 2005. £8,800. Cohen M, Taylor C, Thomson M.
9. Sheffield Children’s Hospital Charity Appeal funding for site-specific running of inflammatory bowel disease multi-centre trial of steroid use v azathioprine plus steroid use with polymeric exclusive enteral nutrition arm. 2004. Thomson M, Taylor C. £20,000
10. Wireless capsule paediatric unit Award. Westfield Foundation, Sheffield. 2004. £35,000. Thomson M, McAlindon M.
11. Neocate and intraluminal impedance in infants. Scientific Hospital Supplies Research Grant 2003. £25,000. Thomson M.
12. Crohn’s and Colitis in Childhood Research Grant for endoscopic innovation 2002. £15,000. Thomson M.
13. Fujinon Endosopic Course Seeding Grant (Annual) £20,000 from 2001 to 2005. Thomson M.
14. Astra Zeneca Endoscopic Teaching Grant, 2001. £5,000. Thomson M.
15. Reckitt Benckeiser Research Fellowship, 2000-2003 £125,000.Thomson M.
16. Astra Foundation Research Grant 1998. £5,000. Thomson M.
17. McDonald’s Family Research Fund 1996. £10,000.  Thomson M.
18. Royal Children's Hospital Foundation Research Grant 1992-3, 1993-4. Resting and total energy expenditure in cystic fibrosis in particular relation to the putative energy-requiring nature of the gene defect and the relative effect of pulmonary inflammation. £65,000. Thomson M, Shepherd R.

Total funding ongoing and to date: £1,082,400
          All as Principal Investigator or joint investigator of two.

5.3     RESEARCH SUPERVISION

  • MD candidate on confocal endomicroscopy, Sheffield Children’s Hospital Bassetlaw research fellow funding. April 06-September 08.
  • MD candidate on intra-oesophageal luminal impedance in neonates and older children. March 2007-March 2009.

5.4     PUBLICATIONS

5.5     Books - in Print

  • “Concise Paediatrics.” pp1-546. Sidwell R and Thomson M. Greenwich Medical Media, Nov 2000.
  • “Q-Base. Paediatric MCQs” Thomson M and Sidwell R. Greenwich Medical Media, 2001.
  • “MCQs for MRCP and DCH 2005” Sidwell R and Thomson M. Greenwich Medical Media. 2003.

 

5.5.1  Chapters – in Print

  • “Disorders of the oesophagus and stomach in infants.” Chapter 2 in Bailliere’s “Clinical Gastroenterology”. 1997;11(3):547-72. Ed: J.A.Walker-Smith.
  • “Dyspepsia in childhood.” for Bailliere’s “Clinical Gastroenterology”. 1998;12(4) . Ed: N Talley.
  • “The Liver in Intensive Care.” N F Shah, M A Thomson. In: “A Manual of Paediatric Intensive Care”. First Edition. Ed: Henderson and Fleming. Publishers: Edward-Arnold. 1999.
  • “Esophagitis” for 3rd Edition of Pediatric Gastrointestinal Diseases. Ed: Walker, Durie, Hamilton, Walker-Smith. Mosby. 2000.
  • “Gastroenterology” in “Concise Paediatrics.” Sidwell R and Thomson M. Greenwich Medical Media, 2000.
  • “Hepatology” in “Concise Paediatrics.” Sidwell R and Thomson M. Greenwich Medical Media, 2000.
  • “Colonoscopy and Enteroscopy in Pediatrics” in “Endoscopy Clinics of North America” Ed V Fox. Saunders. 2001.
  • “The Diverticular Disease in the Young Adolescent” in “Bailliere’s Best Practice & Research Clinical Gastroenterology” Ed: M Camm, Emmanuel A, Cohen R. 2002.
  • “Esophagitis” for 4th Edition of Pediatric Gastrointestinal Diseases. Ed Walker, Durie, Hamilton, Walker-Smith, Sanderson. Mosby. 2004.
  • “Colonoscopy and Enteroscopy” for 4th Edition of Pediatric Gastrointestinal Diseases. Ed Walker, Durie, Hamilton, Walker-Smith, Sanderson. Mosby. 2004.
  •  “Colonoscopy:  practical guide”. In: “Endoscopy in children.” Murphy M, Cadranel S, and Winter H. 2006.
  • “Endoscopy training”. In: “Endoscopy in children.” Murphy M, Cadranel S, and Winter H. 2006.
  • “Endoscopic anti-reflux procedures”. In: “Endoscopy in children.” Murphy M, Cadranel S, and Winter H. 2006.
  • “Enteroscopy in children”. In: “Endoscopy in children.” Murphy M, Cadranel S, and Winter H. 2006.
  • “Pediatric Wireless Capsule Endoscopy”. In: Atlas of Wireless Capsule Endoscopy. Ed: 2006.
  •  “Development, Anatomy and Physiology of the Esophagus” Wylie and Hyams. 2007. Elsevier.

 

5.6     Books – in Press

  • “Paediatrics for Medical Students” Sidwell R and Thomson M. Royal Society of Medicine Press. 2007.
  • “Concise Paediatrics.” pp1-583. Second Edition. Sidwell R and Thomson M. Cambridge University Press. March 2007.

 

5.6.1  Chapters – in Press:

    • “Gastroenterology”. In: Paediatrics for Medical Students. Sidwell R and Thomson M. Cambridge University Press. In press.
    • “Hepatology”. In: Paediatrics for Medical Students. Sidwell R and Thomson M. Cambridge University Press. In press.
    • “Nutrition”. In: Paediatrics for Medical Students. Sidwell R and Thomson M. Cambridge University Press. In press.
    • “Laryngo-pharyngeal reflux”. In: A Textbook of Modern Paediatric ENT Practice. Ed: Graham J, Scadding G, Bull P. In press.
    • “Esophagitis.” In: 5th Edition of Pediatric Gastrointestinal Diseases. Ed: Walker, Durie, Hamilton, Walker-Smith, Sanderson. Mosby. In press.
    • “Colonoscopy and Enteroscopy.” In: 5th Edition of Pediatric Gastrointestinal Diseases. Ed: Walker, Durie, Hamilton, Walker-Smith, Sanderson. Mosby. In press.
    • “Innovations and Advances in Interventional Endoscopy.” In: 5th Edition of Pediatric Gastrointestinal Diseases. Ed: Walker, Durie, Hamilton, Walker-Smith, Sanderson. Mosby. In press.
    • “Diagnostic endoscopy and ileo-colonoscopy in inflammatory bowel disease” In: Pediatric Inflammatory Bowel Disease. Ed: Marmula P et al. In press.
    • “Diagnostic endoscopy and ileo-colonoscopy in inflammatory bowel disease” In: Pediatric Inflammatory Bowel Disease. Ed: Walker –Smith, Branski. In press.
    • “High magnification chromo-endoscopy.” In: Atlas of Confocal Endomicroscopy. Ed: Keislich R. In press.
    • “Gastroesophageal reflux and rhinosinusitis.” In: Otolarngology in Pediatrics. In press.

      5.7 Refereed Journals – in Print

      5.7.1  Refereed Journals - in Print – Original Articles

      1. “Salvage” endoscopic mucosal resection in the colon using a retroflexion gastroscope dissection technique: a prospective analysis. Hurlstone DP, Sanders DS, Thomson M, Cross SS. Endoscopy. 2006(Sep);38(9):902-6. J

      2. Long polar fimbriae and tissue tropism in Escherichia coli O157:H7. R Fitzhenry, S Dahan, A Torres, Y Chong, R Heuschkel, S Murch, M Thomson, J Kaper, G Frankel, A Phillips. Microbes and Infection. 2006;8(7):1741-9. J

      3. Systemic vasculitis: a cause of indeterminate intestinal inflammation. Brogan PA, Malik M, Shah N, Kilday JP, Ramsay A, Shah V, Murch SH, Thomson MA, Walker-Smith JA, Lindley KJ, Milla PJ, Dillon MJ. J Ped Gastroenterol Nutr. 2006;42(4):405-415. J

      4. Acid and non-acid gastro-oesophageal reflux in neurologically impaired children: Investigation with the Multiple Intraluminal Impedance Procedure. R Del Buono, TG Wenzl, D Rawat, M Thomson. J Ped Gastroenterol Nutr. 2006;43(3):331-335. P

      5. Colonic And Duodenal Flat Adenomas In Children With Classical Familial Adenomatous Polyposis. Cohen M,  Taylor C,  Thomson M, Donatone J, Quijano G,  Drut R. J Internat Surg Pathol. 2006;14(2):133-40. J

      6. Improved nutritional recovery on an elemental diet in Zambian children with persistent diarrhoea and malnutrition. Amadi B, Mwiya M, Chomba E, Thomson M, Chintu C, Kelly P, Walker-Smith J. J Trop Pediatr. 2005 Feb;51(1):5-10. J

      7. The Influence of Gaviscon Infant or placebo on gastro-oesophageal reflux in infants: Investigations with the Intraluminal Multiple Electrical Impedance Procedure (IMP). R Del Buono, T G Wenzl, G Ball, S Keady, M Thomson. Arch Dis Child. 2005;90(5):460-3. P

      8. Antibody prophylaxis for children undergoing percutaneous endoscopic gastrostomy. Rawat D, Srivistava A, Thomson M. J Paediatr Gastroenterol Nutr. 2005 Feb;40(2):234-5. P

      9. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease. Thomson M, Fritscher-Ravens A, Afsal N, Hall S, Swain P. Gut. 2004;53(12):1745-50. P

      10. Early interactions of Salmonella enterica serovar typhimurium with human small intestinal epithelial explants. Haque A, Bowe F, Fitzhenry RJ, Frankel G, Thomson M, Heuschkel R, Murch S, Stevens MP, Wallis TS, Phillips AD, Dougan G. Gut. 2004;53(10):1424-30. J

      11. Spontaneous TH1  cytokine production by intraepithelial but not circulating  T cells in infants with or without food allergies. Miguel A Pérez-Machado, Paul Ashwood, Franco Torrente, Camilla Salvestrini, Rosalind Sim,  Michael A Thomson,  John A Walker-Smith, Simon H Murch. Allergy. 2004;59:346-53. J

      12. Diagnostic role of upper gastrointestinal endoscopy in pediatric inflammatory bowel disease. Castellaneta SP, Afzal NA, Greenberg M, Deere H, Davies S, Murch SH, Walker-Smith JA, Thomson M. J Pediatr Gastroenterol Nutr. 2004;39(3):257-61. P

      13. Focal-enhanced gastritis in regressive autism with features distinct from Crohn's and Helicobacter pylori gastritis. Torrente F, Anthony A, Heuschkel RB, Thomson MA, Ashwood P, Murch SH. Am J Gastroenterol. 2004;99(4):598-605. J

      14.High dose azathioprine in children with IBD. Fuentes D, Torrente F, Keady S, Thirrupathy K, Thomson MA, Walker-Smith JA, Murch SH, Heuschkel RB. Alimentary Pharmacology and Therapeutics. 2003;17:913-21.J

      15. Use of unlicensed and off-label medications in paediatric gastroenterology with a review of the commonly used formularies in the UK. A Dick, S Keady, F Mohamed, S Brayley, M Thomson, BW Lloyd, R Heuschkel, NA Afzal.Alimentary Pharmacology and Therapeutics.  2003; 17: 1–5.J

      16. Human intestinal tissue tropism of intimin epsilon O103 Eschericia coli. Fitzhenry R, Stephens M, Jenkins C, Wallis T, Heuschkel R, Murch S, Thomson M, Frankel G, Phillips A. FEMS Microbiology. 2003. J

      17. A consistent pattern of minor immunodeficiency and subtle entropathy in children with multiple food allergy. F Latcham, F Merino, A Lang, J Garvey, MA Thomson, JA Walker-Smith, S Davies, A Phillips, S Murch. J Pediatr. June 2003. J

      18. Reduced transforming growth factor- I 1-producing T cells in the duodenal mucosa of children with food allergy. M Perez-Machado, P Ashwood, M Thomson, F Latcham, R Sim, J Walker-Smith, S Murch. Eur. J. Immunol. 2003 Aug; 33(8): 2307-15. J

      19. Intestinal lymphocyte populations in children with regressive autism: evidence for extensive mucosal immunopathology. Ashwood P, Murch S, Anthony A, Pellicer A, Torrente F, Thomson M, Walker-Smith J, Wakefield A. J Clin Immunol. 2003;23(6):504-17. J

      20. Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism. F Torrente, P Ashwood, R Day, N Machado, R Furlano, A Anthony, S Davies, A Wakefield, MA Thomson, JA Walker-Smith, SH Murch.  Molecular Psychiatry. 2002;7(4):375-82.J

      21. Potential viral pathogenic mechanism for new variant inflammatory bowel disease. V Uhlmann, C M Martin, O Sheils, L Pilkington, I Silva, A Killalea, S H Murch, M Thomson, J A Walker-Smith A J Wakefield, JJ O'Leary. Molecular Pathology. 2002;7(4):383-7. J

      22. Treatment of oesophageal strictures in childhood. Afsal N, Lloyd-Thomas A, Albert D, Thomson M. The Lancet. 2002;359:1032. P

      23. Tissue tropism of enteropathogenic Escherichia coli strains belongingto theO55 serogroup. RJ Fitzhenry, S Reece, LR Trabulsi, R Heuschkel, S Murch, M Thomson, G Frankel, AD Phillips. Infection and Immunity. June 2002. J

      24. Upregulated eotaxin expression and T-cell infiltration in the basal and papillary epithelium in cow’s milk associated reflux oesophagitis. AM Butt, SH Murch, C-L Ng, P Kitching, SM Montgomery, AD Phillips, JA Walker-Smith, MA Thomson. Archives of Disease in Childhood. 2002;86:0-6. P

      25. Esophageal pH monitoring and impedance measurement: a comparison of two diagnostic tests for gastroesophageal reflux. Wenzl T, Moroder C, Trachterna M, Thomson M, Silny J, Heimann G, Skopnik H. Journal of Pediatric Gastroenterology and Nutrition. 2002;34:519-23. P

      26. Refeeding syndrome: case report and a review of the literature. Afzal N, Addai S, Fagbemi A, Thomson M, Murch S, Heuschkel R. Clinical Nutrition. Accepted July 2002. J

      27. Lymphocytic colitis, with CD8 and gd T cell infiltration and epithelial damage, in children with autism. Furlano R, Anthony A, Day R, Brown A, McGarvey L, Thomson M, Davies S, Berelowitz M, Forbes A, Wakefield A, Walker-Smith J, Murch S. Journal of Pediatrics. 2001;138:366-72. J

      28. Intestinal and systemic infection, HIV, and mortality in Zambian children with persistent diarrhea and malnutrition. Journal of Pediatric Gastroenterology and Nutrition. 2001;32(5):550-4.J

      29. Orthotopic liver transplantation with poor neurological outcome in valproate-associated liver failure. Thomson MA, Shepherd R, Lynch S, Strong R, Marsh W. Transplantation Proceedings. 2000;32(1):200-3.

      30. Entero-colitis and immunodeficiency in children with developmental disorders. Wakefield A, Anthony A, Murch S, Thomson M, Montgomery S, Davies S, O’Leary J, Berelowitz M, Walker-Smith J. American Journal of Gastroenterology. 2000;95(9):2285-95. J

      31. Neoral cyclosporin preparation and prevention of chronic rejection. Liver Transplantation and Surgery. van Mourik I, Thomson M, Kelly D. 1999(Mar);5(2):107-11.J

      32. Low-dose intravenous azathioprine may be effective in the management of acute fulminant colitis complicating inflammatory bowel disease. Casson D, Davies S, Thomson M, Lewis A, Walker-Smith J, Murch S. Alimentary Pharmacology and Therapeutics. 1999;13:891-5.

      33. Are endoscopic biopsies of small bowel as good as suction biopsies for the diagnosis of enteropathy? Thomson M, Kitchen P, Jones A, Phillips A. Journal of Pediatric Gastroenterology and Nutrition. 1999; 29(4):438-41. P

      34. Crohn’s disease or intestinal tuberculosis? Salvatore S and Thomson M. Inflammatory Bowel Disease Monitor. 1999; 1(2):59-61. P

      35. Ileal lymphoid nodular hyperplasia, non-specific colitis and pervasive behavioural disorder in children. Wakefield A, Anthony A, Day R, Brown A, McGarvey L, Casson D, Thomson M, Davies S, Berelowitz M, Murch S, Walker-Smith J. The Lancet. 1998(Feb);351:637-41. J

      36. General mitochondrial cytopathy is an absolute contraindication to orthotopic liver transplant in childhood. Rapid communication. Thomson M, McKiernan P, Buckels J, Mayer D, Kelly D. Journal of Pediatric Gastroenterology and Nutrition. 1998;26:478-81. P

      37. Efficacy of Neoral in the immediate postoperative period in children post-liver transplantation. van Mourik I, Thomson M, Kelly D. Liver Transplantation and Surgery. 1998(Nov);4(6):491-8. J

      38. Resting energy expenditure, pulmonary inflammation, and genotype in the early course of  cystic fibrosis. MA Thomson, RW Wilmott, C Wainwright, B Masters, PJ Francis, RW Shepherd. Journal of Pediatrics. 1996;129:367-73. P

      39. Measured vs predicted resting energy expenditure in infants: a need for reappraisal. Thomson M, Bucolo S, Quirk P, Shepherd RW. Journal of Pediatrics. 1995; 126:21-7. P

      40. Nutritional growth retardation is associated with defective lung growth in cystic fibrosis: a preventable determinant of progressive pulmonary dysfunction. MA Thomson , P Quirk, CE Swanson, BJ Thomas, PJ Francis, RW Shepherd. Nutrition. 1995; 11(4):1-5.P

      41. Control of group C meningococcal disease in Australian Aboriginal children by mass rifampicin chemoprophylaxis and vaccination. MC Pearce, JW Sheridan, DM Jones, GW Lawrence, DM Murphy, B Masutti, C McCosker, V Douglas, D George, A O’Keefe, M Thomson, B Gorman, D Hansman, PS Hill. The Lancet.1995(July); 346:20-23. J

      42. Canine-human transmission of Gastrospirillum hominis. MA Thomson, P Storey,
      R Greer, Cleghorn GJ. Short report. The Lancet. 1994;343:1605-07.P

      43. Persistent wheezing and gastroesophageal reflux in infants. Eid N,  Shepherd RW, Thomson MA. Pediatric Pulmonology. 1994; 18:39;P

      44. The effect of dexamethasone therapy on the pattern and incidence of infection in pre-term babies - a prospective controlled study. Ng F,Thomson M,Dear P. Archives of Disease in Childhood. Jan 1990.J

      • 5.7.2  Refereed Journals - in Print – Reviews

      1. Impedance-pH monitoring: paediatric and infant patient experience. Wenzl T, Thomson M. Logopedics Phoniatrics Vocology. 2005(Aug);30(Suppl 1):18-20.P
      2. Paediatric gastro-oesophageal reflux: non-GI manifestations. Thomson M. Logopedics Phoniatrics Vocology. 2005(Aug);30(Suppl 1):23-6.P
      3. Developments in the management of GOR. M Thomson. MIMS Advances. 2004;2:9-10.P
      4. Paediatric gastro-oesophageal reflux in ENT practice. Rawat D, Thomson M. ENT News. 2003;12(1):52-6.P
      5. The pediatric esophagus comes of age. Thomson M. Journal of Pediatric Gastroenterology and Nutrition. 2002;34:S40-S45.P
      6. Management of Uncomplicated Reflux and Regurgitation in Infants and Young Children.  Thomson M. Clinical Nutrition. 2002;11(2);1-7.P
      7. Advances in endoscopy and other diagnostic techniques: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. Olives JP, Bontems P, Costaguta A, Fritscher-Ravens A, Gilger M, Narkewickz M, Ni YH, Spolidoro J, Thomson M; European Society for Paediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2004;39 Suppl 2:S589-95.J
      8. Diarrhoea in infants and children. Afzal N, Thomson M. The Journal of Family Healthcare. 2002;12(6):146-150. P
      9. Reflux: causes and treatments. Thomson M. The Journal of Family Healthcare. 2002;12(6) Supplement:6. P
      10. Constipation in childhood. Afsal N, Thomson M. Prescriber’s Journal. 2001;12(10):101-7.P
      11. Helicobacter pylori: the story so far. Thomson M. Invited Editorial. British Medical Journal. 1999;7209:541.P
      12. Gastro-oesophageal reflux in infants and children. Thomson M. Family Medicine. 1998. P
      13. The economic cost of traveller's diarrhoea.(Lead article). Thomson MA, Booth IW. Pharmacoeconomics. 1996;9(5):382-91.P

      5.8 Refereed Journals – in Press

      5.8.1 Refereed Journals – in Press – Original Articles

      1. Three year efficacy of endoscopic fundoplication in children. Thomson M, Afsal N, Fritscher-Ravens A, Antao B. J Pediatr Gastroenterol Nutr. 2006. (In press). P

      2. Medium term safety and clinical efficacy of endoscopic fundoplication in relation to laparoscopic fundoplication in children. Thomson M, Afsal N, Fritscher-Ravens A, Antao B. J Laparoscop and Advanced Surg Techniques. 2006. (In press).P

      3. Wireless capsule endoscopy in childhood: diagnostic capability. Thomson M, Shawis R, Furman M, Antao B. J Laparoscop and Advanced Surg Techniques . 2006. (In press). P

      4. Achieving R0 resection in the colorectum using Endoscopic Submucosal Dissection: a technical feasibility study in the United Kingdom. Hurlstone DP, Thomson M, Atkinson D. British J Surg. 2006 (In press).J

      5. Polyethylene glycol 3350 plus electrolytes for chronic constipation in children: a double blind, placebo controlled, crossover study. M A Thomson, H R Jenkins, W M Bisset, R Heuschkel, D S Kalra, M R Green, D C Wilson, M Geraint. Arch Dis Child. 2006 (In press).P

      6. Endoscopic mucosal resection for flat neoplasia in chronic ulcerative colitis:
      can we change the endoscopic management paradigm? Hurlstone DP, Sanders D, Lobo A, Cross S, Thomson M, McAlindon M. Gut. 2006 (In press).J

      7. Pediatric Ileocolonoscopy Training: Acquisition of Endoscopic Skill Must Be Nurtured and Objectively Assessed Within a Formalised Pediatric Framework. Hinds R, Thomson M. J Pediatr Gastroenterol Nutr. (In press) P

      8. The acquisition of competence in paediatric ileo-colonoscopy with virtual endoscopy training. Thomson M, Heuschkel R, Murch S, Donaldson N, Hinds R. J Ped Gastroenterol Nutr. 2006 (In press). P

      9. Olympus Lucera High Resolution Vascular Ectasia Mapping In Combination With The Type V Crypt Pattern For The Invasive Depth Estimation and Nodal Disease Estimation In Paris Type II Colorectal Cancers: A Comparative Prospective Analysis To 20MHz Ultrasound. Hurlstone DP, Sanders D, Thomson M, McAlindon M. J Clin Gastroenterol. 2006 (In press).J

      10. Effect of an amino acid-based milk Neocate on gastro-oesophageal reflux in infants assessed by combined intraluminal impedance/pH. Thomson M, Wenzl TG, Fox AT, Del Buono R. Pediatric Asthma, Allergy & Immunology. 2006;19(4): xx-xx. P

      11.  Massive gastrointestinal haemorrhage in isolated intestinal Henoch-Schonlein purpura with response to intravenous immunoglobulin infusion. A Fagbemi, F Torrente, A Hilson, M Thomson, R Heuschkel, S Murch. Eur J Pediatr
      . 2006 (In press). J

      12. The detection and treatment of early flat and depressed colorectal cancer using high-magnification-chromoscopic colonoscopy: a change in paradigm for Western Endoscopists? Hurlstone DP, Thomson M, Sanders DS. Dig Liv Dis. 2006 (In press).J

      13. Percutaneous endoscopic gastrostomy and gastro-oesophageal reflux in neurologically impaired children. M Thomson,TG Wenzl, D Rawat, G Ball, R Heuschkel, R Del Buono. J Ped Gastroenterol Nutr. 2006 (In press). P

      14. Wireless Capsule Endoscopy in Children: A Study to Assess Diagnostic Yield in Small Bowel Disease in Paediatric Patients. M Furman, A Fristcher-Ravens, M Mylonaki, P Swain, M Eltumi, R Heuschkel, S Murch, M Thomson. J Ped Gastroenterol Nutr. 2006 (In press). P

      15. High Magnification Chromoscopic Colonoscopy in Ulcerative Colitis: a valid in vivo optical biopsy tool. D P Hurlstone, M Thomson, D Sanders,  M McAlindon, AJ Lobo, S Cross. Endoscopy. 2006 (In press).J

      16. A randomized control study of pan-chromoscopy guided endomicroscopy vs. conventional white light endoscopy and quadrantic biopsies for the detection and characterization of IN and colitis associated cancer in chronic ulcerative colitis. Hurlstone DP, Cross SS, McAlindon ME, Lobo AJ, Thomson M, Cross SS. Endoscopy. 2006 (In press). J

      17. Topical application of Mitomycin-C in oesophageal strictures. Rosseneu S, Afzal N, Yerushalmi B, Ibarguen-Secchia E, Lewindon P, Cameron D, Mahler T, Schwagten K, Köhler H, Lindley K, Thomson M. Journal of Pediatric Gastroenterology and Nutrition. In press.

      5.8.2  Refereed Journals – in Press – Reviews

      1. Adverse reactions to cow’s milk in paediatrics. Fox A, Thomson M. In: Journal of Clinical Allergy. In press.                                                                                                                                                                     P
      2. Recent developments in small bowel endoscopic examination. Sidhu R, Thomson M. In: Journal of Pediatric Gastroenterology and Nutrition. In press.                                                                             P
      3. Drug bio-pharmacology in the small bowel in children. Johnson T, Thomson M. In: Journal of Pediatric Gastroenterology and Nutrition. In press.                                                                                                     J
      4. Endoscopic anti-reflux approaches in children. Antao B, Thomson M. In: Journal of Pediatric Gastroenterology and Nutrition. In press.                                                                                                      P
      5. Use of mitomycin C in the treatment of gastrointestinal strictures. Antao B, Thomson M. In: Journal of Pediatric Gastroenterology and Nutrition. In press.                                                                             P
       

      5.9     Refereed Conference Papers – in Print/Press, and
      5.10    Non-Refereed Abstracts, Reports & other Publications – in Print

      Letters:

      1. Gaviscon Infant is effective symptomatically in infant reflux-associated symptoms. M Thomson. Arch Dis Child. 2005. P
      2. Helicobacter pylori. The story so far. Thomson M. Letter. British Medical Journal. Jan 2000.  P
      3. Autism, inflammatory bowel disease, and MMR vaccine. Murch S, Thomson M, Walker-Smith J. The Lancet. 1998(March);351:908. J
      4.Canine-human transmission of Gastrospirillum hominis. MA Thomson, P Storey,
      R Greer, Cleghorn GJ. Letter. The Lancet. 1994;344:1097-98.  P

      Published abstracts and conference papers:

      1. A new high lipase pancreatic enzyme supplement in cystic fibrosis: greater efficacy of nitrogen, fat, and energy absorption. Thomson MA,Clegg J,Shepherd RW. Journal of Pediatric Gastroenterology and Nutrition. Dec 1992.

      2. The body cell mass and altered protein energy metabolism in cystic fibrosis. Abstract. Thomson MA, Bucolo S, Thomas BJ, Holt T, Shepherd RW. Pediatric Pulmonology.1993(Sep); Supplement 9:286.

      3. Further evidence that nutritional growth retardation is associated with defective lung growth in cystic fibrosis: a preventable determinant of progressive pulmonary dysfunction.
      Abstract. Thomson MA, P Quirk, C Swanson, B Thomas, P Francis, Shepherd RW. Pediatric Pulmonology.1993(Sep); Supplement 9:286.

      4. Measuring individual energy requirements in CF infants: inaccuracy of predictive equations and validation of heart rate monitoring. Abstract. M A Thomson, R W Shepherd, R Greer, Bucolo S. Pediatric Pulmonolgy.1994(Sep); Supplement 10:276.

      5. Measuring individual energy requirement in infants: inaccuracy of predictive equations and validation of heart rate monitoring. Abstract. M.A.Thomson, S. Bucolo, R.W.Shepherd. Proceedings of the Nutrition Society. 1995; 54(2):109A.

      6. Orthotopic liver transplantation is unsuccessful for valproate-associated liver failure in childhood : a need for critical risk-benefit appraisal in the use of valproate. Thomson MA, McLaughlin D, Eadie M, Lynch S, Strong R, Shaw B, Shepherd RW, Marshall W. Abstract. Journal of Pediatric Gastroenterology and Nutrition. 1995; 20(4):451.

      7. Factors affecting nutrition in early CF: resting energy expenditure, pulmonary inflammatory markers, body composition, and genotype in a neonatally-screened population. Thomson MA, Greer R, Masters B, Cleghorn G, Wilmott R, Francis PJ, Shepherd RW. Proceedings of the Nutrition Society. 1996;55(2):180A.

      8. Exclusion of generalised mitochondrial cytopathy before liver transplant in fulminant hepatic failure. Thomson M, McKiernan P, Buckels J, Mayer D, Kelly D. Journal of Pediatric Gastroenterology and Nutrition. 1996;22(40):432A.

      9. Is Neoral an effective alternative immunosuppressant drug in children post liver transplant? Journal of Pediatric Gastroenterology and Nutrition. 1996;22(4):434A.

      10. Functionally significant secondary inflammation occurs in a primary epithelial enteropathy. Murch S, Graham A, Vermault A, Thomson M, Phillips A, Walker-Smith J. Journal of Pediatric Gastroenterology and Nutrition. 1997;24(4):467A.

      11. A role for intravenous azathioprine in acute fulminant colitis complicating paediatric IBD. Casson D, Thomson M, Walker-Smith J, Murch S. Journal of Pediatric Gastroenterology and Nutrition.  1997;24(4):475A.

      12. Functionally significant secondary inflammation occurs in a primary epithelial enteropathy. Murch S, Graham A, Vermault A, Thomson M, Phillips A, Walker-Smith J. Journal of Pediatric Gastroenterology and Nutrition. 1997;24(4):467.

      13. Ileal lymphoid nodular hyperplasia, non-specific colitis and regressive behavioural disorder: a new syndrome? Wakefield A, Murch S, Anthony A, Linnell J, Casson D, Malik M, Berelowitz M, Dhillon P, Thomson M, Harvey P, Valentine A, Davies S, Walker-Smith J. Journal of Pediatric Gastroenterology and Nutrition. 1997;25(S1):S47.

      14. Initial trial of N-acetyl glucosamine in children with chronic inflammatory bowel disease. Murch S, Salvatore S, Heushkel R, Thomson M, Davies S, French I, Walker-Smith J. Gut. 1998;42(suppl 1):A9.

      15. Histological comparison of recto-sigmoid and full colonoscopic biopsies in the assessment of inflammatory bowel disease in childhood. Deere H, Casson D, Thomson M, Davies S. Gut. 1998;42(Suppl 1):A55.

      16. Autistic enteropathy: a new inflammatory bowel disease? Wakefield A, Murch S, Anthony A, Linnell J, Thomas J, Berelowitz M, Dhillon P, Thomson M, Davies S, Walker-Smith J. Gut. 1998;42(Suppl 1):A85.

      17. Persistent measles virus (MV) infection and immunodeficiency in children with autism, ileo-colonic lymphonodular hyperplasia and non-specific colitis. Wakefield A, Anthony A, Schepelmann S, Kawashima H, Sim R, Khan K, Murch S, Thomson M, Thomas J, Walker-Smith J. Gut. 1998;42(Suppl 1):A86.

      18. Constitutively reduced production of TGF beta 1 by mucosal CD8+ lymphocytes in chldren with cow’s milk sensitive enteropathy. Perez-Machado M, Thomson M, Walker-Smith J, Murch S. Gastroenterology. 1999;116:A571.

      19. Ileo-colonic lymphoid nodular hyperplasia (LNH) is associated with immunodeficiency in children with developmental disorders (DD). Murch S, Anthony A, Thomson M, Montgomery S, Berelowitz M, Walker-Smith J, Wakefield A. Gut. 1999;44(Suppl 1):A127.

      20. Ileo-colonic lymphoid nodular hyperplasia (LNH) is associated with immunodeficiency in children with autistic spectrum disorders (ASD). Murch S, Anthony A, Thomson M, Montgomery S, Berelowitz M, Walker-Smith J, Wakefield A. Gastroenterology. 1999;116;A568.

      21. Autistic enterocolitis: quantitative histopathology of a new-variant inflammatory bowel disease (IBD). Anthony A, Murch S, Davies S, Thomson M, Sim P, O’Leary J, Montgomery S, Berilowitz M, Walker-Smith J, Wakefield A. Gut. 1999;44(Suppl 1):A127.

      22. Upper gastrointestinal involvement in children with inflammatory bowel disease: incidence, localisation and contribution to diagnosis. Archives of Disease in Childhood. April 2000.

      23. A Placebo-Controlled Trial of Azathioprine Therapy in Moderate to Severe New-Onset Colitis. DH Casson, N Shah, RB Heuschkel, S Keady, MA Thomson, SM Montgomery, S Davies, JA Walker-Smith, SH Murch. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s16.

      24. Upper Gastrointestinal Involvement in Children with Inflammatory Bowel Disease: Incidence, Localisation and Contribution to Diagnosis. S Castellenata, M Greenberg, H Deere, S Murch, J Walker-Smith, M Thomson. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s16.

      25. Role of Surgery in Paediatric Crohn’s Disease. A Magoffin, A Lewis, S Murch, M Thomson, J Walker-Smith. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s78.

      26. Foregut Inflammation is Underdiagnosed in Cyclical Vomiting Syndrome. NF Shah, MA Thomson, JA Walker-Smith, VV Smith, KJ Lindley, PJ Milla.. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s126.

      27. Evidence at Protein and mRNA Level of Reduced TH3 Lymphocytes in Multiple Food Allergy. MA Perez-Machado, Pashwood, R Sim, MA Thomson, JA Walker-Smith, SH Murch. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s127.

      28. Distinct Immunological Features of Children with Multiple Food Allergy. F Latcham, F Merino, C Winter, A Lang, J Garvey, MA Thomson, JA Walker-Smith, AD Phillips, SH Murch. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s138.

      29. Enteropathy with T Cell Infiltration and Epithelial IgG Deposition in Autism. F Torrente, N Machado, M Perez-Machado, R Furlano, M Thomson, S Davies, A Wakefield, J A Walker-Smith, SH Murch. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s140.

      30. Upregulated Eotaxin Expression and T Cell Infiltration in the Basal Esophageal Epitheliam in Cow’s Milk-Associated Reflux Esophagitis. AM Butt, SH Murch, Chai-Li Ng, P Kitching, SM Montgomery, AD Phillips, JA Walker-Smith, MA Thomson. Journal of Pediatric Gastroenterology and Nutrition. 2000; 31:s244.

      31. Omeprazole in the first two years of life for gastrooesophageal reflux disease: a dose finding study with dual channel pH monitoring. Furman M, Thomson M.
      J Pediatr Gastroenterol Nutr 2001; 32 (3): 356

      32. Intraluminal imedance technique – application to paediatric gastro-oesophageal reflux. Thomson M, Wenzl T, DelBuono R. Fifth International Bioploymer Conference Proceedings. October 2001.

      33. Intestinal tissue tropism determinants in O55:H6 EPEC. Phillips A, Fitzhenry R, Reece S, Heuschkel R, Murch S, Trabulsi L, Frankel G. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      34. Investiating enterohaemorrhagic eschericia coli (EHEC): human intestinal tissue tropism. Phillips A, Fitzhenry R, Heuschkel R, Murch S, Thomson M, Frankel G. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      35. Azathioprine therapy at diagnosis of severe IBD leads to mucosal healing. Fuentes D, Torrente F, Thomson M, Murch S, Heuschkel R. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      36. Azathioprine with IV loading in 107 children with moderate to severe IBD. Its use and impact on height and weight. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      37. TGF-β and IFN-γ response to polymeric enteral nutrition therapy in acute Crohn’s disease in children. Fagbemi A, Afzal N, Hay C, Ashwood P, Torrente F, Thomson M, Heuschkel R, Murch S. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      38. Focal lymphocytic gastritis occurs in regressive autism, and shows features distinct from Crohn’s disease. Torrente F, Ashwood P, Anthony A, Thomson M, Heuschkel R, Murch S. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      39. A new treatment for oesophageal strictures. Afzal N, Albert D, Lloyd-Thomas A, Thomson M. Journal of Pediatric Gastroenterology and Nutrition. May 2002.

      40. Intraluminal impedance assessment in the neurologically compromised child. Archives of Disease in Childhood. April 2002.

      41. Enteral nutrition treats children with colonic Crohn’s disease more effectively if the ileum is also involved. Afzal NA, Fagbemi A, Arnaud-Battandier F, Paintin M, Thomson M, Walker-Smith JA, Murch S, Heuschkel R, Fell JM. Archives of Disease in Childhood. April 2002.

      42. Clinical and mucosal responses to a new casein based enteral feed containing a higher ratio of n-3:n-6 fats and lower level of total saturated fatty acids for treatment of acute Crohn’s disease in children. Afzal NA, Shergill-Bonner R, Arnaud-Battandier F, Paintin M, Murch S, Thomson M, Heuschkel R, Fell J. Clinical Nutrition May 2002.

      43. Intraluminal impedance and a double blind placebo-controlled study of Gaviscon Infant in GOR in infants. DelBuono R, Keady S, Ball G, Thomson M. J Ped Gastroenterol Nutr. October 2002.

      44. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease. Gut. March 2003.

      46. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease. Thomson M, Afsal N, Fritscher-Ravens A, Swain P. Archives of Disease in Childhood. 2003;88(s1):A16.

      47. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease. Gastroenterology. April 2003.

      48. Endoscopic gastroplication for the treatment of paediatric gastro-oesophageal reflux disease. Thomson M, Afsal N, Fritscher-Ravens A, Swain P. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):559.

      49. Cow’s milk induces T-cell proliferation and mucosal mast cell degranulation with neural tropism in an in-vitro organ culture model. Torrente F, Fitzhenry R, Heuschkel R, Thomson M, Murch S. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):527.

      50. Paediatric endoscopy unit establishment and nursing practice development. Ratnarajah A, Brennan M, Shine M, Thomson M. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):531.

      51. Use of methotrexate in childhood Crohn’s disease. Rawat D, Furman M, Fagbemi A, Torrente F, Keady S, Thomson M, Murch S. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):542.

      52. Wireless capsule endoscopy in small bowel disease in paediatrics: a study to assess the diagnostic yield. Furman M, Mylonaki M, Fritshcer-Ravens A, Swain P, Heuschkel R, Murch S, Thomson M. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):544.

      53. Intraluminal impedance pH monitoring - ? the platinum standard. Ball G, Del Buono R, Wenzl T, Thomson M. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):559.

      54. Assessment of reflux in neurologically inpaired children using the multiple intraluminal impedance procedure. Thomson M, Rawat R, Ball G, Wenzl T, Del Buono R. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):559.

      55. Evidence of CFTR dysfunction in children with recurrent pancreatitis. Corpino M, Jaffe A, Thomson M, Milla P, Lindley K. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):564.

      56. Immunohistochemical characteristics of allergic colitis in children. Torrente F, Barabino A, Heuschkel R, Thomson M, Murch S. Journal of Pediatric Gastroenterology and Nutrition. 2003;36(4):566.

      57. Torrente F, Fitzhenry R, Heuschkel R, Thomson M, Murch S. Cow’s milk induces T cell proliferation and mucosal mast cell degranulation with neural tropism in an in vitro organ culture model. Journal of Pediatric Gastroenterology and Nutrition. 2003; 36: 527.

      58. Rawat D, Furman M, Fagbemi A, Torrente F, Keady S, Thomson M, Murch S, Heuschkel R. Use of methotrexate in childhood Crohn’s disease. Journal of Pediatric Gastroenterology and Nutrition. 2003; 36: 542.

      59. Rawat DJ, Srivastava A, Keady S, Heuschkel R, Murch S, Thomson M. Antibiotic prophylaxis for children undergoing percutaneous endoscopic gastrostomy (PEG). Gastroenterology  2003; 124: A431.

      60. Thomson M, Del Buono R, Wenzl T, Ball G, Murch S, Heuschkel R. Percutaneous endoscopic gastrostomy and gastro-oesophageal reflux in the neurologically impaired. Arch Dis Child 2004; 89 (suppl 1): A13.

      61. Salvestrini C, Heuschkel RB, Thomson MA, Murch SH. Desquamative enterocolitis – a cause of severe persistent diarrhoea related to epidermolysis bullosa-pyloric atresia syndrome. Journal of Pediatric Gastroenterology and Nutrition. 2004; 39 (S1): S274-5.

      62. Kirkham S, Heuschkel R, Murch S, Thomson M. Disseminated histoplasmosis associated with sclerosing cholangitis. Journal of Pediatric Gastroenterology and Nutrition. 2004; 39 (S1): S259.

      63. Furrman M, Mylonaki M, Swain P, Hyer W, Eltumi M, Heuschkel R, Murch S, Firtscher-Ravens A, Thomson M. Study of efficacy of wireless capsule endoscopy in a paediatric cohort. Journal of Pediatric Gastroenterology and Nutrition. 2004; 39 (S1): S286.

      64. Antao B, Bishop J, Shawis R, Thomson M. Clinical application and diagnostic yield of wireless capsule endoscopy in children. Laparoscopic and Advanced Surgical Techniques. 2006:16(2):A194.

      65. Antao B, Fritscher-Ravens A, Hall S, Afzal N, Ashwood P, Swain P, Thomson M. Long-term outcome of endoluminal gastroplication (Endocinch) in children. Laparoscopic and Advanced Surgical Techniques. 2006:16(2):A196.

      66. Thomson M, Heuschkel R, Murch S, Hinds R. The acquisition of competence in paediatric ileo-colonoscopy with virtual endoscopy training. Journal of Pediatric Gastroenterology and Nutrition. May 2006.

      67. Antao B, Fritscher-Ravens A, Hall S, Afzal N, Ashwood P, Swain P, Thomson M. Long-term outcome of endoluminal gastroplication (Endocinch) in children. Journal of Pediatric Gastroenterology and Nutrition. May 2006.

      68. Cohen M, Bishop J, Walker J, Taylor C, Thomson M. Investigation of molecular alterations of paediatric Barrett’s oesophagus using laser microdissection on  paraffin-embedded endoscopic biopsies. Histology. September 2006.

      69. Venkatesh K, Taylor C, Cohen M, Gerrard M, Thomson M. Helicobacter associated fundal adenocarcinoma – is it causal? Gastroenterology. October 2006.

      70. Venkatesh K, Taylor C, Cohen M, Gerrard M, Thomson M. Helicobacter associated fundal adenocarcinoma – is it causal? Journal of Pediatric Gastroenterology and Nutrition. October 2006.

      5.11               Non-Refereed Abstracts, Reports & other Publications including Invited presentations and lectures for which conference proceedings have been published:

       

      1. Eighth Annual North American Cystic Fibrosis Conference in Dallas, October 1993:
      "A case of allergic broncho-pulmonary aspergillosis with cavitating lung lesions".
      2. British Society for Paediatric Gastroenterology and Nutrition. 20th January 1995.
      "Elevated risk of infection with Helicobacter pylori in staff and residents of a residential care facility."
      3. British Paediatric Association. 21st - 24th March 1995.
      "Elevated risk of infection with Helicobacter pylori in staff and residents of a residential care facility."
      4. British Paediatric Association. 21st - 24th March 1995. Plenary session.
                    “Ortotopic liver transplantation is unsuccessful for valproate-associated liver failure       
                    in childhood: a need for critical risk-benefit appraisal in the use of valproate.”
      5. The Second Royal Free Hospital Combined Medical/Surgical GI Masterclass - “The Foregut”. 2nd November 1995.
      “State of the art lecture:The Paediatric Foregut”.
      6. British Association of Parenteral and Enteral Nutrition. 4th-6th December 1995.
      “Factors affecting nutrition in early CF: resting energy expenditure, pulmonary inflammatory markers, body composition, and genotype in a neonatally-screened population.”
      7. British Paediatric Association. 16th-19th April 1996.
      “Factors affecting nutrition in early CF: resting energy expenditure, pulmonary inflammatory markers, body composition and genotype in a neonatally-screened population”.
      8. British Paediatric Association. 16th-19th April 1996.
      “Pharmacodynamic/pharmacokinetic profiles of a new water-miscible prepartion of cyclosporin for immunosuppression immediately following orthotopic liver transplant.”
      9. European Society of Paediatric Gastroenterolgy and Nutrition. 8th June 1996.
      “Exclusion of generalised mitochondrial cytopathy before liver transplant in fulminant hepatic failure”.
      10. 5th Congress of the Asian PanPacific Society of Pediatric Gastroenterolgy and Nutrition. 10th April 1997.
      “Immunological characteristics of reflux oesophagitis - is there a recognizable pattern?”
      11. British Society for Paediatric Gastroenterology and Nutrition. 25th January 1998.
      “Are endoscopic biopsies of small bowel as good as suction biopsies for the diagnosis of enteropathy?”
      12. Royal College of Paediatrics and Child Health 4th Meeting York. 11th April 2000.
      “Upper gastrointestinal tract involvement in children with inflammatory bowel disease: incidence, localisation and contribution to diagnosis.”
      13. International Food Allergy Symposium. Regent’s College, London. 2nd May 2000. “Allergic oesophagitis”.
      14. Invited Lecture. British Dermatology Annual Meeting, Portsmouth. 19th May 2000. “The emerging face of paediatric gastroenterology”.
      15. Invited Guest Lecture. Italian Society of Gastroenterology. “Endoscopy in childhood IBD”. Bari, Italy. 27th Oct 2000.
      16. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. Southampton. 15th Sep 2002.
      17. Fifth International Biopolymer Conference. Intraluminal impedance technique – application to paediatric gastro-oesophageal reflux. Thomson M, Wenzl T, DelBuono R. Sep 2001.
      18. Invited Guest Lecture. Endoscopic fundoplication. 6th Foregut Masterclass in Adult Gastroenterology. Royal Free Hospital. Jan 2002.
      19. Invited Guest Lecture. St Mary’s Hospital, London. 25th Feb 2002.Inflammatroy bowel disease in childhood.
      20. Invited Guest Lecture. Endoscopy in childhood. National OPD Sister’s Meeting. London. 13th April 2002.
      21. RCPCH Annual Spring Meeting. Intraluminal impedance assessment in the neurologically compromised child. York. 16th April 2002.
      22. ESPGHAN 35th Annual Meeting. A new treatment for caustic oesophageal strictures.Taormina, Sicily. 12th June 2002.
      40. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. Dublin. 7th March 2002.
      41. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. Bolton. 15th May 2002.
      42. Invited Guest Lecture. Intraluminal impedance in infant GOR. Reckitt Benckiser Symposium. Hull 9th May 2002.
      43. Grand Round Royal Free Hospital. Intraluminal impedance and Gaviscon Infant in infant GOR. Royal Free Hospital. 12th June 2002.
      44. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. Southampton. 13th June 2002.
      45. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. Royal London Adult Gastroenterology Grand Round. Royal London Hospital. 13th June 2002.
      46. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. London. 28th June 2002.
      47. Invited Guest Lecture. Infant Nutrition Symposium. Diagnosis and management of infant GOR. Edinburgh. 28th October 2002.
      48. 13th Annual Paediatric Gastroenterology Course. GOR and respiratory disease: causative or fellow travellers. Royal Free Hospital. 3rd December 2002.
      49. BSPGHAN Winter Meeting. Antibiotic prophylaxis for PEG placement in paediatrics. Dublin 24th January 2003.
      50. BSPGHAN Winter Meeting. Wireless capsule endoscopy in paediatric GI investigation. Dublin 24th January 2003.
      51. Grand Round Royal Free Hospital. Wireless capsule endoscopy in paediatric GI investigation. January 29th 2003.
      52. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Percutaneous gastrostomy – theory.
      53. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Endoscopic aspects of GOR.
      54. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      PEGs – practical aspects.
      55. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Barrett’s oesophagus in children.
      56. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Endoscopic anti-reflux procedures in children.
      57. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Endoscopy in IBD in children.
      58. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Wireless capsule endoscopy in childhood.
      59. South American Paediatric Gastroenterology Meeting, Brazil April 2003.
      Alleric oesophagitis in infancy.
      60. Tenth Colon Masterclass Royal Free. January, 2003.
      Paediatric IBD: modern endoscopic aspects.
      61. S African GI Masterclass, Cape Town. 18th February 2003.
      Gastro-oesophageal reflux in infants and children.
      62. S African GI Masterclass, Cape Town. 18th February 2003.
      Recurrent abdominal pain in children revisited.
      63. Paediatric GI allergy meeting, SHS, Royal College of Physicians, London. 2nd March 2003. Allergic oesophagitis.
      64. Dublin Children’s Hospital Grand Round. 11th March 2003. Paediatric endoscopic anti-reflux procedures.
      65. British Society of Gastroenterology. Birmingham. 25th March 2003. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease.
      66. Laryngopharyngeal Reflux Symposium. Nottingham. 1st April 3003. Intraluminal oesophageal impedance and LPR in children.
      67. Royal College of Paediatrics and Child Health Spring Meeting. York. 8th April 2003. The Vomiting Baby: Personal Practice Session.
      68. Royal College of Paediatrics and Child Health Spring Meeting. York. 8th April 2003. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease.
      69. ENT Invited Lecture. Great Ormond Street Hospital. London. 29th April 2003. LPR, ENT, and GOR: Advances.
      70. Royal Free Annual GP Seminar on Medical Advances. 29th April 2003. Recurrent abdominal pain in children revisited.
      71. Royal Free Annual GP Seminar on Medical Advances. 29th April 2003.
      GOR in infants and children.
      72. British-Italian Paediatric Gastroenterology Meeting. Lucca, Italy. 9th May 2003. Paediatric Endoscopy Today and Tomorrow.
      73. American Society of Gastrointestinal Endoscopy. Florida. 21st May 2003. Oral distinction presentation: Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease.
      74. European Society of Paeditric Gasatroenterology Hepatology and Nutrition. Prague. 7th June 2003. Endoscopic fundoplication for the treatment of paediatric gastro-oesophageal reflux disease.
      75. GP Endoscopist Annual Meeting. Brussels. 14th June 2003. Paediatric Endoscopy Today.
      76. Nottingham Queen’s Hospital Grand Round. 26th June 2003. Paediatric Endoscopy Today and Tomorrow.
      77. Kingston Hospital Grand Round. 7th July 2003. GOR advances in paediatrics.
      78. European Oesophageal Conference. 2nd September 2003. Paris. Endoscopic fundoplication for paediatric gastro-oesophageal reflux.
      79. Foregut Masterclass. Royal Free Hospital. 15th Jan 2004. Advances in Diagnosis in GOR.
      80. Foregut Masterclass. Royal Free Hospital. 15th Jan 2004. Endoscopic treatment for GORD.
      81. Middlesex SpR gastroenterology meeting training day. 29th Jan 2004. Paediatric manifestations of GORD.
      82. First Wireless Capsule UK Group Meeting. 30th Jan 2004. WCE for children.
      83. BSG. 22nd March 2004. Endoscopic fundoplication for paediatric GORD.
      84. Royal Society of Medicine, Paediatric Gastroenterology day. 27th April 2004. Advances in paediatric endoscopy.
      85. British Paediatric Otolaryngology Course, Institute of Child Health. 14th May 2004. Advances in paediatric GORD.
      86. American Society of Gastrointestinal Endoscopy. Invited Lecture. 16th May 2004. Advances in the endoscopic treatment of strictures.
      87. 6th International Laryngopharyngeal Conference. 19th May 2004. Paediatric manifestations of GOR and the use of intraluminal impedance.
      88. 2nd World Congress of Paediatric Gastroenterology, Paris. 3rd July 2004. Post-graduate Course. Endoscopic polyp therapy.
      89. Annual Belgian Paediatric Gastroenterology Meeting. 26th November 2004. Advances in paediatric endoscopy.
      90. 15th Annual Paediatric Gastroenterology Course. 29th November 2004. GORD and intraluminal oesophageal impedance.
      91. 6th Annual Masterclass in Paediatric Endoscopy. 1st December 2004. Training in paediatric endoscopy.
      92. 6th Annual Masterclass in Paediatric Endoscopy. 2nd December 2004. Advanced management of strictures by endoscopy in childhood.
      93. Winter meeting BSPGHAN. 28th January 2005. Advances in endoscopic management of GI strictures.
      94. First Controversies in Paediatric Gastroenterology and Hepatology Meeting. Birmingham. 4th February 2005. Endoscopic management of oesophageal reflux disease.
      95. Trent Paediatric Combined Meeting. Invited lecture. 10th February 2005. Advances in paediatric gastro-oesophageal reflux.
      96. BSG. Birmingham. Invited Lecture. 14th March 2005. Endoscopic Management of gastro-oesophageal reflux.
      97. 7th International Laryngopharyngeal Conference. York. 6th April 2005. Recent advances in gastro-oesophageal reflux in paediatrics.
      98. 7th International Laryngopharyngeal Conference. York. 7th April 2005. Impedance in gastro-oesophageal reflux inchildren.
      99. American Society of Gastrointestinal Endoscopy. Chicago. 17th  May 2005. Endoscopic management of GORD in children.
      100. ESPGHAN Annual meeting. Porto. Post-graduate Course. 2nd June 2005. Advances in paediatric therapeutic endoscopy.
      101. Paediatric Gastro Club Meeting, Midlands. 27th September 2005. Invited Lecture. Recurrent Abdominal Pain of Chldhood.
      102. SHS Paediatric Allergy Study Day, London. 21st September 2005. Intraluminal Impedance in Childhood Reflux Disease.
      103. Inaugural Paediatric Hands-On Colonoscopy Course. Six Lectures. 19th-20th September 2005. Sheffield Children’s Hospital.
      104. Reflux Symposium, Mead Johnson. Bury. 5th July 2005. Update on GOR in childhood.
      105. First Northern Ireland Paediatric Allergy Study Day. 10th June 2005. Allergic reflux and GI diseases in childhood.
      106. Trainee GI Meeting, Nottingham. 10th July 2005. Advances in paediatric endoscopy.
      107. Bassetlaw Grand Round. 17th June 2005. Recurrent Abdominal Pain.
      108. North West Paediatric GI Trainee Meeting. 7th October 2005. Achalasia.
      109. Chesterfield Grand Round. 12th October 2005. Chronic diarrhoea in childhood.
      110. United European Gastroenterology Week. Copenhagen. 18th October 2005. Invited Lecture: Allergic and eosinophilic oesophagitis.
      111. United European Gastroenterology Week. Copenhagen. 18th October 2005.
      Invited Lecture: Lower GI endoscopy in children.
      112. Invited Lecture to Combined Paediatric Group of Sheffield Paediatric Consultants. 19th October 2005. Gastro-oesophageal reflux in children.
      113. Conjoint North-West Paediatric Gastroenterology Trainee Training Meeting. 19th October 2005.Gastrointestinal Endoscopy in Paediatrics.
      114. Invited Lecture: 24th Brazilian Paediatric Gastroenterology Week. Port Allegre, Brazil. 3rd November 2005.  Eosinophilic oesophagits.
      115. Invited Lecture: 24th Brazilian Paediatric Gastroenterology Week. Port Allegre, Brazil. 3rd November 2005.  Interventional paediatric endoscopy.
      116. Invited Lecture: 24th Brazilian Paediatric Gastroenterology Week. Port Allegre, Brazil. 5th November 2005.  Advances in Paediatric Endoscopy.
      117. Invited Lecture: 24th Brazilian Paediatric Gastroenterology Week. Port Allegre, Brazil.  5th November 2005.  Gastro-oesophageal reflux in children.
      118. Invited Lecture: 24th Brazilian Paediatric Gastroenterology Week. Port Allegre, Brazil. 5th November 2005. Peptic ulcer disease in children.
      119. Invited Lecture: Second European Wireless Capsule Castle Course. 18th November 2005.  Paediatric applications of the wireless capsule endoscopy technique.
      120. Invited Lecture: Second International Paediatric Endoscopy Course. Al Mansour, Eqypt. 19th November 2005. Advances in Paediatric Endoscopy.
      121. Invited Lecture: Second International Paediatric Endoscopy Course. Al Mansour, Eqypt. 19th November 2005. Endoscopic treatment of gastro-oesophageal reflux.
      122. Invited Lecture: Second International Paediatric Endoscopy Course. Al Mansour, Eqypt. 19th November 2005. Endoscopy in paediatric inflammatory bowel disease.
      123. Invited Lecture: Second International Paediatric Endoscopy Course. Al Mansour, Eqypt. 19th November 2005. Allergic manifestations of paediatric GI disease.
      124. Invited Lecture: SHS symposium. York. 25th November 2005. Allergic reflux and other GI allergic diseases.
      125. Invited Lecture: Royal Free 8th Masterclass in Live Paediatric Endoscopy. Diabetes, coagulopathy, and antibiotic prophylaxis in paediatric endoscopy.
      126.  Invited Lecture: Royal Free 8th Masterclass in Live Paediatric Endoscopy. Advances in paediatric endoscopy.
      127. Invited Lecture: Royal Free 8th Masterclass in Live Paediatric Endoscopy. Algorithms in paediatric endoscopy.
      128. Invited Lecture: Royal Free 8th Masterclass in Live Paediatric Endoscopy. Paediatric Barrett’s oesophagus.
      129. Invited Lecture: SHS symposium. London. 9th December 2005. Allergic reflux and other GI allergic diseases.
      130. First Hands-On Endoscopic Fundoplication Course. Sheffield. 9th January 2006. Endoscopic fundoplication in paediatric practice.
      131. Invited Lecture. Inflammatory Bowel Disease Advances Symposium. Newcastle. 18th January 2006. The place of  wireless capsule endoscopy in inflammatory bowel disease management.
      132. Winter meeting of BSPGHAN. Newcastle 19th January 2006. Place of virtual training in paediatric colonoscopy training.
      133. First Hands On Paediatric Endotherapeutic Course. 6th February 2006. Polypectomy and endomucosal resection techniques and pitfalls.
      134. First Hands On Paediatric Endotherapeutic Course. 6th February 2006. Stricture and achalasia endo-therapy.
      135. First Hands On Paediatric Endotherapeutic Course. 6th February 2006. Practical use of pneumatic balloon devices.
      136. First Hands On Paediatric Endotherapeutic Course. 6th February 2006. Variceal and non-variceal endotherapy.
      137. First Hands On Paediatric Endotherapeutic Course. 6th February 2006. Advances in Paediatric Endotherapy.
      138. 4th Bill Owen Surgical Symposium. Invited Lecture. Royal College of Surgeons. 2nd March 2006. Minimally invasive anti-reflux procedures in childhood.
      139. Otolaryngology in the 21st Century. ENT section of Royal Society of Medicine. Invityed Lecture. 3rd March 2006. Advances in GOR and LPR.
      140-6. Second Paediatric Hands-On Colonoscopy Course. Six Lectures. 6th-7th Marc 2006. Sheffield Children’s Hospital.
      147. BSG. Keynote Lecture. Birmingham. 22nd March 2006. Advances in paediatric reflux diagnosis.
      148. First Intraluminal Impedance Meeting. Invited Lecture. Birmingham. 30th March 2006. Paediatric state-of-the-art impedance analysis: experience to date.
      149. Second European Castle Wireless Capsule Hands-On Course. Invited Lecture. 7th April 2006. WCE in children.
      150. Barnsley DGH Grand Round. Invited Lecture. 18th April 2006. Diarrhoea that goes on.
      151. Sheffield adult-paediatric GI Grand Round. 21st April 2006. State of the art in intraluminal impedance reflux analysis.
      152. Mead-Johnson Education Meeting. Crewe. 3rd May 2006. Advances in paediatric GORD.
      153. SCH Grand Round. 4th May 2006. Helicobacter pylori and gastric adenocarcinoma.
      154. Neonatal Grand Round. Jessop’s, Sheffield. 12th May 2006.Esomeprazole and neonatal reflux: analysis with impedance and video-cardio-respiratory analysis.
      155. ESPGHAN. Dresden. 8th June 2006. 36 month follow up of endoscopic fundoplication in children.
      156. ESPGHAN. Dresden. 9th June 2006. Virtual model training in paediatric colonoscopy.
      157. EACCI. Vienna. Invited Lecture. 12th June 2006. GOR and rhino-sinusitis: Pro.
      158. European CF Meeting. Invited Lecture. 17th June 2006. Endoscopic approaches to reflux management in cystic fibrosis.
      159-164. Third Hands-On Paediatric Colonoscopy Course. Six lectures. Sheffield. 19th-20th June 2006.
      165-170. Fourth Hands-On Paediatric Colonoscopy Course. Six lectures. Sheffield. 3rd -4th July 2006.
      171. North Trent Regional Training Day: Live GI Endoscopy. Hallamshire Hospital, Sheffield. 28th June 2006. Endoscopic anti-reflux procedures.
      172. Sheffield Feeding Course. Ryegate Hospital. Invited Lecture. 5th July 2006. Recent advances in GOR in childhood and relevance to the feeding process.
      173. Annual GI Allergy Meeting, SHS, British Institute of Architects, London. 17th August 2006. Update on allergic GORD.
      174-7. Fifth Hands-On Paediatric Colonoscopy Course. Four lectures. Sheffield. 18th-19th September 2006.
      178. Third Paediatric GI Symposium. Great Ormond Street Children’s Hospital, London. 22nd September 2006. Helicobacter pylori in childhood.
      179. Annual General Meeting, Sheffield Children’s Hospital. 26th September 2006. Paediatric Endoscopy in the 21st Century.
      180-85. Sixth Hands-On Paediatric Colonoscopy Course. Six lectures. Sheffield. 2nd-3rd October 2006.
      186. Birmingham Children’s Hospital Grand Round. 18th October 2006. Advances in paediatric endoscopic diagnostics and therapeutics.
      187. Doncaster DGH. 20th October 2006. Recurrent abdominal pain of childhood.
      188. United Euopean Gastroenterology Week. Invited Speaker. 24th October 2006. Eosinophilic esophagitis.
      189. Indo-British Paediatric GI Inaugural Meeting. 26th October 2006. Advanced Paediatric diagnostic and therapeutic endoscopy in childhood.
      190. Hungarian Paediatric Gastroenterolgy Conference. 10th-11th November 2006. Endoscopic approaches to reflux in paediatrics.
      191. Hungarian Paediatric Gastroenterolgy Conference. 10th-11th November 2006. Advanced endo-diagnostic techniques in children.
      192. Sheffield Community Paediatric Teaching Programme. 15th November 2006. Common paediatric GI conditions.
      193. Fourth Basic Wireless Capsule Endoscopy Course. Durham. 16th November 2006. WCE in paediatrics.
      194. First European Wireless Capsule Endoscopy Course. Durham. 18th November 2006. Advanced WCE in paediatrics.
      195. Allergic GI conditions in Childhood: Chairman for Workshop and lecture day. Nottingham. 21st November 2006. GI allergic manifestations.
      196. Allergic GI conditions in Childhood: Chairman for Workshop and lecture day. Nottingham. 21st November 2006. Allergic GI case presentations and workshop.
      197. Ninth Royal Free Paediatric Endoscopy Masterclass. 26th-30th November 2006. Endoscopic images, description and lesion recognition.
      198. Ninth Royal Free Paediatric Endoscopy Masterclass. 26th-30th November 2006. Developmens in paediatric endoscopy of the oesophagus.
      199. Ninth Royal Free Paediatric Endoscopy Masterclass. 26th-30th November 2006. The theory of loops in colonoscopy and practical solutions.
      200. Ninth Royal Free Paediatric Endoscopy Masterclass. 26th-30th November 2006. Wireless endoscopy in young children?
      201. Ninth Royal Free Paediatric Endoscopy Masterclass. 26th-30th November 2006. Advanced diagnostic procedures.
      202. Edinburgh Children’s Hospital GI Course. 7th December 2006. Gastro-oesophageal reflux in childhood: an update and endoscopic management potential.
      203.  Royal Society of Medicine GORD Paediatric Symposium. 11th January 2007. Gastro-oesophageal reflux symptoms in older children.
      204. Royal Society of Medicine GORD Paediatric Symposium. 11th January 2007. Non-surgical treatment of GORD in childhood.

      5.12    Research in Progress (Brief Description)
      1. Intraluminal oesophageal impedance and pH in the assessment of gastro-oesophageal reflux and temporal causal relationship with cardio-respiratory events in a randomised placebo-controlled study of esomeprazole in preterm and term neonates. Head of multi-disciplinary research team. MD supervision.

      2. Confocal endomicroscopy in the non-biopsy assessment of mucosal pathology in paediatric enteropathy, ileo-colitis, and polyp syndromes. MD supervision.

      3. Interventional therapeutic anti-reflux endoscopy for the treatment of gastro-oesophageal reflux of childhood.

      4. Endoscopic pyloromyotomy for the treatment of pyloric stenosis in childhood.

      5. Prophylactic intervention with the anti-fibroblastic agent mitomycin C for the prevention of caustic ingestion-associated oesophageal stricture formation in children.

      6. Use of a novel propulsion agent, tegaserod, in the treatment of GORD in infants and children.

      7. Double balloon enteroscopy in the assessment of small bowel mucosal pathology in children.

      8. Genomic mapping in Barrett’s oesophagus in childhood.